Prothioconazole is a broad-spectrum triazolethione fungicide developed and launched in 2004. It has the functions of protection, treatment and eradication, and has good systemic properties. It is mainly used to prevent and control many diseases of cereal crops (such as wheat, barley, etc.), rape, peanuts, rice, bean crops and so on. It can be used as a foliar spray or as a seed treatment. Efficacy tests show that prothioconazole not only effectively controls wheat scab, but also effectively reduces gibberellin.
Thioconazole has developed rapidly since its launch in 2004 and has now become the second largest fungicide market and the largest variety of fungicides for grains.
The current main markets for prothioconazole are still Europe and the United States, with the Asian market being smaller.
Mechanism of action and application
Compared with traditional triazole fungicides, prothioconazole introduces a thione structure into the molecular structure. Its mechanism of action is to inhibit the demethylation of the 14-position lanosterol or 2,4-methylenedihydrolanosterol, the precursor in fungi, that is, demethylation inhibitors (DMIs). It not only has good systemic activity, excellent protective treatment and eradication activity, but also has a long lasting effect.
Through a large number of field tests, the results show that prothioconazole has a broader spectrum of bactericidal activity than traditional triazole fungicides, and not only has good biological toxicity to control targets. It is also safe for crops and the environment, has good disease prevention and treatment effects, and significantly increases production.
Because prothioconazole has the characteristics of high activity, broad spectrum and relatively safety, it is widely used in wheat, soybeans, rapeseed, rice, peanuts, sugar beets, etc. around the world. For example, it has a broad bactericidal spectrum and has a good control effect on diseases, and has excellent control effects on almost all fungal diseases on cereals. Such as powdery mildew, scab, sheath blight and rust, etc. It can effectively prevent and control soil-borne diseases of rape and peanuts as well as major leaf diseases, such as gray mold, brown spot, black spot, rust and black shank. According to research, the conventional dosage of prothioconazole is around 200g/hm2. At this dosage, the activity is better than or equal to conventional fungicides, such as epoxiconazole, tebuconazole, cyprodinil, etc.
Prothioconazole is currently registered on a variety of crop pathogens in different regions, but its dosage is mainly used on wheat (including wheat, barley, oats, buckwheat, etc.) and soybeans, especially wheat and soybeans.
Market Expectation
Prothioconazole has the advantages of broad bactericidal activity, good systemic activity, high protection, treatment and eradication activity, and long validity period. In the international market, prothioconazole has outstanding effects on powdery mildew, scab, sheath blight and rust in crops such as soybeans and wheat and has been used for many years. Prothioconazole can also deal with resistance caused by long-term use of single-agent and compound preparations such as carbendazim, thiram, thiophanate-methyl, epoxiconazole, prochloraz, tebuconazole, and hexaconazole. At present, prothioconazole has become a drug recommended by the Agricultural Technology Center for the prevention and treatment of "two diseases" of wheat. It has good market application prospects and is worthy of promotion and scientific application.
