Introduction to Sulfoxaflor
Sulfoximine is a sulfoximine pesticide developed by Dow AgroSciences (now Corteva) in the United States. It acts on insect acetylcholine receptors and is an acetylcholine receptor agonist.
Sulfoxaflor is highly effective against sucking pests such as aphids, planthoppers, and whiteflies, and because of its novel chemical structure, it has no cross-resistance with neonicotinoid insecticides. It can be used for resistance management to prevent and control pests that are resistant to neonicotinoids, pyrethroids, organophosphorus and carbamate insecticides. Thanks to its excellent control effect and broad control spectrum, sales of sulfoxaflor have basically maintained a rapid growth trend since its launch, with a compound annual growth rate of 18.3% from 2014 to 2019.
Mechanism of action and application
Sulfoxaflor is a nicotinic acetylcholine receptor agonist. After binding to the receptor, the intrinsic activity of the receptor is activated, the receptor channel opens, and Na+ outside the cell membrane flows into the cell, controlling the functions of the nervous system through electrical signal transmission between nerve cells. It has systemic conduction activity. After administration, it conducts from bottom to top through the xylem of the plant.
The International Action Committee on Insecticide Resistance (IRAC) classifies sulfoxaflor as the 4C (sulfoximines) subgroup of Group 4, and it is the only active ingredient in this subgroup.
Sulfoxaflor has both stomach poisoning and contact killing effects. It has a broad insecticidal spectrum and is effective against a variety of pests with sucking mouthparts. Such as Hemipteran pests, Lygus bugs, Homoptera pests such as aphids, scale insects, planthoppers, whiteflies, etc. It is suitable for a variety of crops, such as citrus, cotton, cabbage, flowers, vegetables and fruit trees. It has excellent control effect against target pests, good quick-acting effect and long-lasting effect. It can be used for resistance management to effectively prevent and control sucking pests with mouthparts that are resistant to neonicotinoids, pyrethroids, organophosphorus and carbamate insecticides.
Summarize
Sulfoxaflor is a sulfoximine pesticide that acts on the acetylcholine receptors of insects. It is systemic and can be absorbed by the stems, leaves and roots of plants. It has a wide insecticidal spectrum, high efficiency, low dosage, long lasting effect, and is particularly effective against piercing-sucking mouthparts pests. Moreover, its chemical structure is novel and has no cross-resistance with neonicotinoid pesticides. It can be used to control pests that are resistant to neonicotinoids, pyrethroids, organophosphorus, and carbamate pesticides. However, sulfoxaflor is highly toxic to bees, so there has been a risk of being banned in recent years. In addition, the domestic patent period is still three to four years, and the production cost of the original drug is relatively high. Many manufacturers want to develop it and are therefore deterred from developing it. However, its unique mechanism of action and efficient insecticidal effect are worthy of the market's expectations.
