Pinoxaden is a new phenylpyrazoline herbicide with a novel structure and unique mechanism of action. It is also an acetyl-CoA carboxylase (ACCase) inhibitor. It is classified as "other herbicides" in the pesticide category. Pinoxaden is a market-leading product and a star product with a high growth rate.
Mechanism of action and characteristics
The mechanism of action of Pinoxaden is an acetyl-Coenzyme A carboxylase (ACCase) inhibitor. When the agent is rapidly absorbed by the stems and leaves of weeds, it is then transmitted to the meristem, inhibiting the activity of acetyl-Coenzyme A carboxylase (ACCase). It blocks the biosynthesis of fatty acids, interferes with cell membrane formation, stops cell growth and division, and destroys the lipid-containing structure of the cell membrane, causing weeds to stop growing and eventually die. Generally, sensitive weeds will stop growing 48 hours after pesticide application, weeds will begin to turn yellow within 1 to 2 weeks, and weeds will die completely within 3 to 4 weeks. However, the degree of weed damage after pesticide application is related to the reaction speed and factors such as climatic conditions, weed species, and growth conditions. Pinoxatad is highly safe for wheat and barley. If applied under adverse conditions, the leaves of wheat and barley may experience temporary chlorosis symptoms, but it will not affect their normal growth, development and final yield.
Pinoxaden will cause phytotoxicity to wheat and barley seedlings (shown as yellow spots on the leaves of wheat seedlings, stagnant growth of wheat seedlings, yellow flowers, slight leaf curling, or aggravation of frost damage to wheat and barley). The higher the dosage, the more serious the damage. However, the symptoms of phytotoxicity will generally gradually disappear 20 to 30 days after application, and ultimately there will be no significant impact on yield. The safety agent ethylpyridyl can usually be added to improve the safety of the product.
The pinoxaden pesticide degrades quickly in the soil, is rarely absorbed by the roots, and has only very low soil activity and has no impact on subsequent crops. At the same time, it has strong resistance to rain erosion, and the weeding effect will not be affected if it rains within 1 hour after application.
Pinoxaden has the following characteristics:
(1) Pinoxatad, herbicides such as aryloxyphenoxypropionates (Fop) and cyclohexenone (Dim) are both ACCase inhibitors. However, because pinoxaden has a new chemical structure, its action site is different.
(2) Pinoxaden is a selective, systemic grass weed herbicide with high efficiency, broad spectrum and quick effect. After application, pinoxaden pesticide can be absorbed by weed leaves and then transferred to the meristem, inhibiting the synthesis of esters in dividing cells. The weeds will soon stop growing, resulting in weed necrosis.
(3) Pinoxatad is a stem and leaf herbicide that is rarely absorbed by plant roots, has little soil activity, and degrades quickly in the soil. It is safe for current crops of wheat, barley and non-target organisms, and has good safety characteristics for subsequent crops and the environment. Symptoms of poisoning appear on weeds 1 to 3 weeks after pesticide application, and the meristematic tissue dies rapidly. It is mainly used to control grass weeds such as foxtail, foxtail grass, barnyard grass, etc. in spring wheat, winter wheat, durum wheat, barley and other grain crop fields.
(4) Pinoxate has good compatibility with other herbicides and can be used in compound or tank mix with most broadleaf weed killers in wheat fields. For example, mixed with 50 g/L difluorosulfonam suspension, 58 g/L difluorosulfonam · azoxystrom suspension, bensulfuron methyl and other buckets to achieve the goal of one-time use to control all weeds in wheat fields. And the suitable application period is wide, it can be applied from the 2-leaf and 1-heart stage of wheat seedlings to the booting stage. The best application period is the 3-5 leaf stage after the emergence of most grassy weeds in the field.
(5) Pinoxaden has excellent control activity against weeds that are resistant to ACCase inhibitors. In particular, the control effect on some malignant grass weeds, such as sedge, Japanese sedge, wild oat, ryegrass, hard grass and chrysanthemum, is close to 100%.
(6) Pinoxaden can effectively control multiflora ryegrass, and the control effect is stable. Multiflora ryegrass is an annual gramineous grass with strong regeneration and reproduction capabilities. It is an excellent grass species for feeding cattle, sheep, pigs, rabbits, geese and other grass-eating livestock and poultry. In pasture-growing areas, affected by man-made activities or soil erosion, multiflora ryegrass gradually migrates to wheat fields and causes damage.
(7) Pinoxaden is not only used in the "cereal" (wheat and barley fields) market around the world to control annual grass weeds. (Such as wild oats, ryegrass, foxtail grass, hard grass, chrysanthemum grass, wheatgrass, Japanese wheatgrass , clotgrass, etc.) Another area of application is in the "non-crop" (lawn and garden) market, especially in Europe and North America. At present, pinoxaden is not focused on the "non-crop" market in other countries and regions, which is also an important development and growth point for pinoxaden in the future.
Outlook
At present, pinoxaden has been launched in all major cereal markets around the world, and since its launch, its market has been showing a growth trend and is still on an upward path. As a domestic enterprise, on the one hand, it can reduce product prices by optimizing the synthesis process and put the original drug or single dose on the EU market; on the other hand, it can actively develop compound dosage forms suitable for domestic and foreign markets. However, since many of its compounds in the European market are still under SPC protection, companies need to pay attention to avoid patent risks.
