Heterocyclic compounds have always been a focus of research and development by pesticide researchers because of their efficient biological activities. Tolfenpyrad is a new type of pyrazole amide insecticide and acaricide. It has the functions of protection, treatment, eradication and penetration, and is non-mutagenic. It is a new type of agricultural insecticide and acaricide with great development potential and market vitality in the pesticide industry.

Mechanism of action
Tolfenpyrad is a new type of pyrazole amide insecticide and acaricide. It has the characteristics of high efficiency, broad insecticidal spectrum, wide application range and quick effect. It is an effective agent that has the functions of killing eggs, inhibiting feeding, inhibiting oviposition and sterilizing. It is widely used for pest control of vegetables, fruit trees, flowers, tea and other crops. Its mechanism of action is to hinder the electron transfer system of the insect's mitochondrial energy metabolism system, hindering electron transfer and preventing the insect's oxidative phosphorylation, so that the insect cannot provide and store energy and die. Therefore, it is also known as mitochondrial electron transport complex inhibitor (METI).

biological activity
Tolfenpyrad is a new type of pyrazole amide insecticide and acaricide. It has the characteristics of high efficiency, broad insecticidal spectrum, large application range, and quick effect. It is an effective agent that has the functions of killing eggs, inhibiting feeding, inhibiting oviposition, and killing bacteria. It is widely used for pest control of vegetables, fruit trees, flowers, tea and other crops. It has a high feeding inhibitory effect on lepidopteran and beetle pests. According to indoor activity measurement, it has high activity against diamondback moth throughout its growth period, from eggs to adults, and inhibits pests from feeding. It has small differences between species in its control effect against aphids in the order Hemiptera and thrips in the order Thripida, and is also effective against resistant pests. The pesticide also has good quick-acting properties. The pests will die soon after their mouthparts are inserted into the crops treated with the pesticide.
When applying tolfenpyrad to control field pests, the effect is best when applied from the hatching stage of pest eggs to the young (nymph) insects. The pure dosage for controlling thrips on eggplants is 7.5-12 g/mu, and the pure dosage for controlling diamondback moth on cruciferous vegetables is 4.5-7.5 g/mu. The dosage is low, and it is better to use the secondary dilution method when preparing the pharmaceutical solution in Chemicalbook. Depending on the severity of the pest, the interval between each application is 7 to 15 days. Since diamondback moth is a pest that easily develops resistance to pesticides, the pesticide should not be used more than twice a season in rotation. The safety interval for cruciferous vegetables is 21 days, and the safety period for eggplant seedlings and leafy vegetables is greater than 3 days. Because tolfenpyrad is toxic to silkworms, fish, bees and other organisms, its use in aquaculture areas near silkworm rooms and mulberry gardens during the flowering period of nectar crops should be prohibited.
Summarize
Tolfenpyrad is famous for its high efficiency, broad spectrum, low toxicity and quick effect. It has the functions of killing eggs, inhibiting feeding, inhibiting spawning and sterilizing, and can play a good role in contact killing. It has a strong control effect on various Lepidoptera, Hemiptera, Carabidae, Hymenoptera, Diptera pests and mites. The effect of this pesticide is rapid, and once sprayed, the pests will die immediately. It also has good control effect on fungal diseases and is the direction of new pesticide development in the 21st century. It is worth noting that tolfenpyrad has a good killing effect on scale insects. Highly toxic organophosphorus products such as methotrexate are the main agents used to kill scale insects. However, as highly toxic pesticides are banned and restricted in countries around the world, tolfenpyrad may become one of its important alternatives. However, this agent also has the disadvantage of being highly toxic to humans and animals, and highly toxic to fish, silkworms, and some natural enemies or beneficial organisms. Therefore, care must be taken when using it and management must be strengthened.







