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Dec 28, 2023

Insect growth regulating insecticide specifically designed to promote rapid molting of lepidopteran pests

Since the advent of dihydrazide insecticides, products such as hydrazide, fenfenozide, chlorfenozide, methoxyfenfenozide, and cyclofenofenozide have been developed, which have gradually been recognized and widely paid attention to in the industry. Methoxyfenozide is a second-generation dihydrazide insect growth regulator discovered by the American company Rohm-Haas (now Corteva) in 1990. The product is produced by Dow AgroSciences and sold around the world, with sales rights for the European market awarded to Bayer.

 

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It is the most effective type of dihydrazide insecticide and has the greatest market potential.

 

Mechanism of action


Methoxyfenozide is a derivative of tebufenozide. In terms of molecular structure, it has one more methoxy group on the benzene ring than tebufenozide, which makes it more biologically active than tebufenozide and has better root systemic absorption. It is more obvious in monocotyledonous crops such as rice. Methoxyfenozide is an ecdysone agonist, which causes lepidopteran larvae to stop feeding and accelerate the molting process, causing the insect to die due to premature molting before maturity.

 

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Methoxyfenozide is highly selective and highly effective against lepidopteran pests. It can be used on crops such as cereals, soybeans, cotton, grapes, citrus, vegetables, corn and ornamental plants to control a wide range of lepidopteran pests, such as noctuidae, cabbage mealybugs, armyworms, leaf rollers and borers.

 

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Methoxyfenozide has no penetrating effect and phloem systemic activity. It works mainly through gastric poisoning. It also has certain contact and ovicidal activities.

 

Applicable crops and control objects


Due to the special mechanism of action of methoxyfenozide, it only targets lepidopteran pests, accelerates molting and aging and affects the reproduction of offspring, thereby killing lepidopteran pests and protecting crops for a long time. Methoxyfenozide can be used on almost all crops to prevent damage from lepidopteran pests.

 

Summarize

 

First, methoxyfenozide is a second-generation dihydrazide insect growth regulator and a biomimetic ecdysone inhibitor. This drug has the opposite mechanism of action to the insecticides that inhibit molting of pests. It can be used to control pests throughout their larval stage. It is generally considered an ideal insecticide due to its high selectivity, resistance to pesticides and environmental friendliness.

 

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Secondly, the resistance of some products in application is increasing year by year, and highly toxic pesticides are gradually withdrawn. The market urgently needs the alternate use of methoxyfenozide and its compound varieties to improve the control effect, or as an effective substitute for some varieties.

 

Thirdly, the registration of methoxyfenozide preparations is increasing year by year, and the broadening of insecticidal applications will provide new market growth drivers for methoxyfenozide. The breakthrough in the production of the original drug will drive down the cost of the original drug, and the product quality will be reduced. The cost-effectiveness advantage will gradually emerge.

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