Recently, the common name of Syngenta Crop Protection’s methoxyacrylate pesticide Flupyroxystrobin was approved by ISO.
IUPAC: (2E)-Methyl 3-methoxy-2-(2-{[4-(trifluoromethyl)-2-pyridyl]oxy}phenyl)acrylate
CAS Name: Methyl (E)-α-(methoxymethylene)-2-[[4-(trifluoromethyl)-2-pyridyl]oxy]phenylacetate
CAS NO.：114077-75-7
Molecular formula: C17H14F3NO4
Active/ingredient: Insecticide (methoxyacrylate)
Structural formula:
Flupyroxystrobin is the first methoxyacrylate insecticide (non-acaricide), discovered by British Imperial Chemical Industries and developed by its successor company Syngenta. It is speculated that its mechanism of action is the same as similar species such as azoxystrobin, picoxystrobin, fluacrypyrim and pyriminostrobin, all of which are respiratory inhibitors of Qo mitochondria.
As an insecticide, flupyroxystrobin has no cross-resistance with pyrethroid insecticides such as permethrin. It also has a synergistic effect on knocking down and killing Anopheles stephensi mosquitoes when combined with 4-trifluoromethylnicotinamide (a metabolite of fluoxenamide).
The creation ideas and synthesis route of Flupyroxystrobin are shown in the figure below:
Source: AgroPages
